The Journal of Toxicological Sciences

The Journal of Toxicological Sciences

The Journal of Toxicological Sciences (J. Toxicol. Sci.) is a scientific journal that publishes research about the mechanisms and significance of the toxicity of substances, such as drugs, food additives, food contaminants and environmental pollutants.

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Published by The Japanese Society of Toxicology

3,096 registered articles
(updated on May 10, 2026)

Online ISSN : 1880-3989
Print ISSN : 0388-1350
ISSN-L : 0388-1350

1.8
2023 Journal Impact Factor (JIF)

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2026 Volume 51 Issue 5

Synergistic toxicity of methylmercury and cadmium through NRF2 suppression and mercury retention Yasukazu Takanezawa, Narumi Suda, Nayu Orimo, Ryosuke Nakamura, Yuka Ohshiro, Shimpei Uraguchi, Masako Kiyono
Ordinal association between cytochrome P450 inhibition and hepatotoxicity severity in rats Nana Uchida, Minami Shibata, Akira Ooka, Ryota Shizu, Jun-ichi Takeshita, Kouichi Yoshinari
Visually evoked potentials as an early indicator of acrylamide-induced visual dysfunction in rats Kensuke Kawamoto, Yukako Shimotsuma, Kazunari Okada, Satoki Fukunaga, Hiroyuki Asano
Effect of zwitterionic liquids on cytochrome P450 and P-glycoprotein Yusuke Kubota, Risa Funaki, Yuto Sana, Takeru Ishizaki, Richard W. Wong, Eishu Hirata, Kosuke Kuroda

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Most viewed articles (April 2026)

1

Gene expression profiling of methapyrilene-induced hepatotoxicity in rat

Released on J-STAGE: February 26, 2008 | Volume 33 Issue 1 Pages 37-50

Takeki Uehara, Naoki Kiyosawa, Mitsuhiro Hirode, Ko Omura, Toshinobu Shimizu, Atsushi Ono, Yumiko Mizukawa, Toshikazu Miyagishima, Taku Nagao, Tetsuro Urushidani
2

Comprehensive molecular docking on the AlphaFold-predicted protein structure proteome: identifying target protein candidates for puberulic acid

Released on J-STAGE: July 01, 2025 | Volume 50 Issue 7 Pages 309-324

Teppei Hayama, Rin Sugawara, Ryo Kamata, Masakazu Sekijima, Kazuki Takeda
3

Characterization of air freshener emission: the potential health effects

Released on J-STAGE: September 10, 2015 | Volume 40 Issue 5 Pages 535-550

Sanghwa Kim, Seong-Ho Hong, Choon-Keun Bong, Myung-Haing Cho
4

Caffeine potentiates the dependence induced by central nervous system depressants contained in over-the-counter medications in mice

Released on J-STAGE: February 01, 2026 | Volume 51 Issue 2 Pages 131-139

Ayaka Yonemura-Hirata, Asuka Kaizaki-Mitsumoto, Satoshi Numazawa
5

Predicting nucleic acid drug-induced nephrotoxicity using a 3D human renal proximal tubule spheroid model

Released on J-STAGE: January 06, 2026 | Volume 51 Issue 1 Pages 75-87

Kaoru Morimura, Etsushi Takahashi, Hayata Maeda, Yukiko Nishioka, Ayano Araki, Hiroshi Mizumoto, Yoichi Jimbo

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■■ Impact factor ■■
2023：1.8
2022：2.0
2021：1.792
2020：2.196
2019：1.737
2018：1.732
2017：1.719
2016：1.436
2015：1.224
2014：1.292
2013：1.378
2012：1.380
2011：1.522
2010：1.893

Related journals

Sister Journal ”Fundamental Toxicological Sciences”

Annual Meeting of the Japanese Society of Toxicology

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