To obtain information on perfusion-related, free, and restricted diffusion in uterine cervical cancer using diffusion-weighted magnetic resonance imaging (DWI) , we analyzed three diffusion components using triexponential function. Twenty-two subjects were evaluated using the DWI with multiple b-values. We derived perfusion-related diffusion, fast free diffusion, and slow restricted diffusion coefficients (
Dp-tri, Df-tri, Ds-tri) obtained from triexponential fitting parameters to DWI data. Moreover, the triexponential analysis was compared with biexponential analysis (
Df-bi and
Ds-bi; fast and slow diffusion coefficients) and monoexponential analysis (
Dm; apparent diffusion coefficient) . In triexponential analysis could well separate combined diffusion coefficient into three diffusion components in cervical cancer, because the order of the diffusion coefficients was
Dp-tri>Df-bi>Df-tri>Dm>Ds-bi>Ds-tri. triexponential analysis makes it possible to noninvasively obtain more detailed diffusion information in patients with uterine cervical cancer.
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