Surface modification of functional polymers onto liposomes is effective strategy to obtain functional liposomes that release drugs at target site or intracellular compartments. Here, design of pH-sensitive liposomes for cell-specific intracellular drug delivery was summarized. Liposomes modified with hyaluronic acid derivatives exhibited selective anticancer drug delivery to CD44-expressing cancer cells. Furthermore, liposomes modified with curdlan derivatives were efficiently recognized by dendritic cells, leading to efficient antigen delivery, activation of dendritic cell and induction of antitumor immunity on tumor-bearing mice. Therefore, functional polymer-modified liposomes are promising for cell-selective cancer chemotherapeutic system or immunotherapeutic systems.

Thermally conductive polymer composites offer new possibilities for the thermal management in electronic devices. An approach of current interest to improve the thermal conductivity of polymer composites is the addition of high thermally conductive fillers with different shape and size. This paper described an overview of the microstructural design techniques for polymer composites with high thermal conductivity, and recent progress and advances that have been made on the enhancement of thermal conductivity of the polymer composites.

In an industrial incinerator, suppression of ash emission is of great importance from a viewpoint of environment preservation. In some of the incinerators, a control plate is equipped to suppress the ashes, where it is designed based on engineers’ experience. The control plate is assumed to recoil the ash particles. On the other hand, effect of the control plate has not been examined sufficiently, and besides behavior of ash particles has not been figured out in the incinerator. This is because the incinerator scale is so large that validation tests cannot be performed. In the present study, a numerical technology is applied to an industrial incinerator to examine the effect of the control plate and to analyze the ash particle behavior. In the numerical simulations modeling of an arbitrary shape wall boundary and large-scale simulation technique are required. In this study, advanced DEM-CFD method is employed, where coarse grain model of the DEM is used as scaling law modeling and signed distance function and immersed boundary method are applied to arbitrary shape wall boundary in the DEM-CFD method. The numerical simulations illustrate that the control plate works effectively, whereas, against all expectations, the ash particles are shown to remain in the incinerator not by collision to wall but by settling on the plate due to vortex.

The choking prevention effect on dense-phase pneumatic conveying has been investigated experimentally while moisture and particle diameter are changed. Consequently, the adhesion force between particles and pipe wall has been increased drastically with increasing of moisture content. However, it has been reduced with ultrasonic in spite of experimental condition. This means the possibility of choking can be removed with ultrasonic vibration. Additionally particle motion on the ultrasonic vibration plate was analyzed. This result showed that particle velocity increases along with particle diameter and moisture content influences on only large-sized particle. This cause was considered that heavy particle which includes a lot of water cannot jump in long distance and water makes the meniscus between particle and wall.

To understand the detail structure of the pulverized coal flame, it is necessary to apply the carefully controlled optical diagnostics because the significant signal disturbance from the fuel particles would reduce the accuracy of data. In this paper, the highlight results obtained by applying shadow Doppler particle analyzer (SDPA) and laser induced incandescence (LII) and time-resolved LII (TiRe-LII) to the pulverized coal flame were summarized.