Bronchial hyperresponsiveness is useful as a marker for diagnosis and management of bronchial asthma. We investigated bronchial hyperresponsiveness using the Astograph method. Furthermore, in recent years, MostGraph has attracted increased attention as a method for analyzing respiratory resistance using oscillometry. Therefore, we compared the two methods and investigated the relationship. We recruited 117 individuals whose data were measured by MostGraph and Astograph from a previous study. The levels of Rrs were significantly correlated with each MostGraph index. SGrs/Grscont showed a weak correlation with indicators other than the Ax (R5: r=0.199, p=0.019, R20: r=0.220, p=0.008, X5: r=−0.179, p=0.037, Fres: r=0.195, p=0.021) . The levels of logPD35Grs, logDmin, and logPD15Grs exhibited weak correlations with X 5, Fres, and Ax (logPD35Grs: X5: r=0.201, p=0.00189, Fres: r=− 0.210, p=0.013, AX: r=−0.169, p=0.049, logDmin: X5: r=0237, p=0.0054, Fres: r=−0.213, p= 0.012, AX: r=−0.177, p=0.038, logPD15Grs: X5: r=0.236, p=0.0056, Fres: r=−0.215, p=0.011, AX: r=−0.174, p=0.043) . The FEV1 and MostGraph indicators were significantly correlated, but no relationship was shown with the FeNO. In conclusion, evaluating the results of airway hyperresponsiveness tests using the FeNO, FEV1, and MostGraph indicators is difficult, but the reactance component may reflect bronchial sensitivity and hyperresponsiveness.
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