Annual Meeting of the Japanese Society of Toxicology

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The 36th Annual Meeting of the Japanese Society of Toxicology

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Organ Toxicity, Metabolism, Method, etc.

An administration of antimicrobial quarternary ammonium compounds (QUAT) caused immunotoxicity to CIR mice

Atsumi Yamaguchi, Tomoko Fujitani, Norio Ohashi, Dai Nakae, Akio Ogata

Session ID: P-39
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4039.0

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Effects of Thyroid Peroxidase Inhibitors on the Immune System –Lymphocyte Subset Analysis and T-cell Dependent Antibody Response -

Motoko Fukui, Seiji Shibata, Shigeru Hisada, Katsura Suzuki, Kouji Ban ...

Session ID: P-40
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4040.0

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Effects of administration stress on peripheral blood lymphocyte subsets in cynomolgus monkeys

Takayuki OKAMURA, Hideki TOKUDOME, Makoto TSUNEMI, Kiyohisa FUKASAWA, ...

Session ID: P-41
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4041.0

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Study of eye irritation testing with a reconstructed cornea model.

Masakazu Katoh, Fumiyasu Hamajima, Takahiro Ogasawara, Ken-ichiro Hata

Session ID: P-42
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4042.0

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Evaluation of drug-induced liver injury in humans by using chimeric PXB mice with highly humanized liver

SHINICHI NINOMIYA, SHINICHIRO NAGATSUKA, GAKU ONISHI, DARINA HYNES, MA ...

Session ID: P-43
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4043.0

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Current Status of Short-term Carcinogenicity Study Using Genetically-engineered Mice -Questionnaire Survey and Literature Research of Japan Pharmaceutical Manufacturers Association-

Shigeo KAWANO, Naoki KATO, Hironori TAKAGI, Hitoshi NISHIDA, Daisaku Y ...

Session ID: P-44
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4044.0

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Establishment of mitochondrial toxicity screening method for drug-induced idiosyncratic liver injury.

Maki Hashimoto, Sayori Tanaka, Naoteru Koseki, Jiro Deguchi, Toru Yama ...

Session ID: P-45
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4045.0

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Usefulness of pursuant to ISCEV protocol ERG in cynomolgus monkeys

Sou WADA, Gou NEGISHI, Masamitsu KAMON, Hideto NAKAMURA, Yumi WAKO, Se ...

Session ID: P-46
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4046.0

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The method for sampling and tissue preparation of the parathyroid glands of miniture pig in toxicity study

Tomomi Soshin, Hirotake Takai, Chie Kato, Etsuko Fujii, Akio Miyoshi, ...

Session ID: P-47
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4047.0

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A Genotoxicity test system based on p53R2 gene expression in human cells (6)

Katsutoshi Ohno, Taisei Mizota, Yukimasa Tanaka-Azuma, Shigeru Nakano, ...

Session ID: P-48
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4048.0

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Appropriate sampling time for histopathological examination for peripheral venous Irritation test of infusion solutions in rabbits

TAKASHI KUWAHARA, SHINYA KANEDA, EMIKO KOHNO, SETSUKO ANAMI

Session ID: P-49
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4049.0

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Rat strain differences in safty pharmacology study of the central nervous system between Sprague-Dawley and Wistar rats

Yoshihisa Nakano, Satomi Kikuchi, Shigeki Matsumoto, Tomokazu Matsusue

Session ID: P-50
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4050.0

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CellCiphr; Cellular Systems Biology Assay for Hepatotoxicity using Human HepG2 cells

Hitomi Fukada

Session ID: P-51
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4051.0

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Importance of PK evaluation to explain the results of carbapenem-induced renal toxicity study in rabbits

Tomokazu Koresawa, Masahiro Nomoto, Chiharu Yoshida, Nayu Mitomi, Yoko ...

Session ID: P-52
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4052.0

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Pregnenolone-16alpha-carbonitrile-mediated protection against lithocholic acid-induced hepatotoxicity and lipid levels

Masaaki Miyata, Fumiaki Sotodate, Masahiro Nomoto, Yasushi Yamazoe

Session ID: P-53
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4053.0

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Involvement of microRNA in Phenobarbital-mediated gene expression

Chiharu MURAKAMI, Satoshi NUMAZAWA, Takemi YOSHIDA

Session ID: P-54
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4054.0

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Investigation of the SAMP8 as a model for decreased drug metabolising ability in the elderly

Hiro Fujisawa, Koutaro Suzuki, Yorifumi Nisihori, Takaya Momiyama, Nor ...

Session ID: P-55
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4055.0

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Evaluation of Induction of Drug Metabolizing Enzyme in Freshly Isolated Dog Hepatocytes

Hiroyuki Murata, Noriko Ninomiya, Saika Deguchi, Makiko Kohno, Toshio ...

Session ID: P-56
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4056.0

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Quantitative assessment of reactive metabolite using dansyl glutathione trap assay

Masanori Kobayashi, Kyoko Kato, Akio Sugiyama

Session ID: P-57
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4057.0

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Inhibition of mitochondrial membrane-bound glutathione transferase by mitochondrial permeability transition (MPT) inhibitors including cyclosporin A

Enkhbaatar Ulziikhishig, Kang Kwang Lee, Sohel Hossain Quazi, Yumiko H ...

Session ID: P-58
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4058.0

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Utility of An in vivo Medium-term Initiation Assay Model using 4 Week-old Rats

Yoshiji Asaoka, Hiroki Sakai, Akihiro Hirata, Jun Sasaki, Masanobu Gor ...

Session ID: P-59
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4059.0

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Twenty six-week repeated toxicity of diheptyl phthalate (DHP) in Rats

Masaki KUNIEDA, Yoshihiko KOBAYASHI, Hirotoshi AKANE, Yoshitomo MOROZU ...

Session ID: P-60
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4060.0

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Posters Applying the Award for Young Scientist

Comprehensive comparison of toxicogenomics data using pathway information

Yoshinobu Igarashi, Yousuke Minowa, Yasushi Okuno, Noriyuki Nakatsu, A ...

Session ID: P-61
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4061.0

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Applicability evaluation of the short-term prediction system for carcinogenicity for SD rats

Fumiyo Saito, Hiroshi Matsumoto, Hirofumi Yokota, Yasushi Minobe, Yosh ...

Session ID: P-62
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4062.0

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Toxicogenomic approach for identifying marker genes of liver toxicity in rat blood.

Masayuki Kanki, Noriyuki Nakatsu, Hiroshi Yamada, Tetsurou Urushidani, ...

Session ID: P-63
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4063.0

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Prediction model construction and marker genes extraction for cholestasis using toxicogenoimcs approach in rats

Daisuke KIGAMI, Takashi MATSUDA, Koutarou TAMURA, Kou OMURA, Masayuki ...

Session ID: P-64
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4064.0

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A Toxicogenomics Approach for Identification of Genomic Biomarkers That Predict Future Onset of Drug-Induced Renal Tubular Injury

Yohsuke Minowa, Takeki Uehara, Chiaki Kondo, Noriyuki Nakatsu, Yasushi ...

Session ID: P-65
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4065.0

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Investigation of biomarkers for estrogenic activity of chemicals in the rat by proteomics analysis

Masafumi Horiuchi, Hidenori Yamanaka, Masahiro Takeyoshi, Yasushi Mino ...

Session ID: P-66
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4066.0

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Species difference in hepatic gene expression profile and blood dehydroepiandrosterone level elicited by o,p'-DDT

NAOKI KIYOSAWA, Joshua Kwekel, Lyle Burgoon, Timothy Zacharewski

Session ID: P-67
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4067.0

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Evaluation of drug-induced hepatotoxicity through metabolic activation by human CYP1A2 and CYP2E1

Yasuyuki TOYODA, Tatsuki FUKAMI, Miki NAKAJIMA, Tsuyoshi YOKOI

Session ID: P-68
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4068.0

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Evaluation of drug-induced hepatotoxicity through metabolic activation by human CYP2C9

Atsushi IWAMURA, Tatsuki FUKAMI, Hiroko HOSOMI, Miki NAKAJIMA, Tsuyosh ...

Session ID: P-69
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4069.0

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Effects of food additives on the activation of pregunane X receptor in newly established reporter cell line, HepG2-PXRLucA3.

Masashi SEKIMOTO, Shinsuke SANO, Kiyomitsu NEMOTO, Akiyoshi NISHIKAWA, ...

Session ID: P-70
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4070.0

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Individual differences in human drug metabolizing enzymes: Relationship between Ames test and gene expression profile

Shuko Hata, Yasuhiro Miki, Shuji Nagasaki, Hironobu Sasano

Session ID: P-71
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4071.0

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Change in the gene expression of hepatic drug-metabolizing enzymes during the process of adjuvant-induced arthritis in rats

Hisakazu SANADA, Masashi SEKIMOTO, Kiyomitsu NEMOTO, Masakuni DEGAWA

Session ID: P-72
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4072.0

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Effects of pregnancy on acetaminophen-induced hepatotoxicity in rats

Yshinaka Urasoko, Masao Takano, Yuri Isagawa, Aikihito Watanabe, Nobuh ...

Session ID: P-73
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4073.0

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Phenobarbital-induced changes in blood coagulation-related parameters in pregnant and lactating rats

satomi shimizu, yuri kidokoro, takumi oishi, takahiro kitazawa, kazuhi ...

Session ID: P-74
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4074.0

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Warfarin-induced changes in blood coagulation parameters in pregnant and lactating rats

Takahiro Kitazawa, Saori Suzuki, Masahiro Mochizuki, Hiroyasu Yoshinag ...

Session ID: P-75
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4075.0

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Simultaneous determination of PBDEs, MeO-PBDEs and OH-PBDEs found in Marine Biota by APCI-LC/MS/MS

Yoshihisa KATO, Syohei OKADA, Kazutaka ATOBE, Futoshi MATSUBARA, Tetsu ...

Session ID: P-76
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4076.0

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Usefulness of urinary Kim-1, Clusterin and Albumin as biomarkers for renal toxicity in rats

Yuko Nagayama, Toru Sekido, Yuki Momozawa, Haruki Tanaka, Emiko Katsur ...

Session ID: P-77
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4077.0

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Development of new simplified analysis method for mitochondrial DNA damage

Akira Onodera, Fumiya Ogita, Asako Kashimura, Megumi Yoshida, Yasuo Ts ...

Session ID: P-78
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4078.0

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In vivo mutagenicity and tumor promotion activity in the livers of rats treated with tocotrienol

Tomoki INOUE, Masako TASAKI, Yuji ISHII, Toshiya OKAMURA, Yuta SUZUKI, ...

Session ID: P-79
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4079.0

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Enhancement of in vivo mutagenicity of MeIQx in the liver of mice treated with CCl₄

Toshiya OKAMURA, Yuji ISHII, Tomoki INOUE, Masako TASAKI, Yuta SUZUKI, ...

Session ID: P-80
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4080.0

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Inhibitory effects of pentachlorophenol, a sulfotransferase inhibitor, on in vivo mutagenicity in the kidneys of gpt delta mice treated with lucidin-o-primeveroside

Yuji Ishii, Toshiya Okamura, Masako Tasaki, Tomoki Inoue, Yukio Kodama ...

Session ID: P-81
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4081.0

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In vitro mammalian chromosomal aberration test of Fullerene-C60

Kyung Taek Rim, Soo Jin Kim, Hae Won Cho, Hyeon Yeong Kim, Jeong Sun Y ...

Session ID: P-82
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4082.0

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Antimutagenic Effects of Ginsenoside Rb1, Rg1 in the CHO-K1 cells treated with the polyaromatic hydrocarbon benzo[a]pyrene with Chromosome aberration test and Comet assay

Kyung Taek Rim, Jong Gyu Kim, Soo Jin Kim, Hyeon Yeong Kim, Jeong Sun ...

Session ID: P-83
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4083.0

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Low dose-treatment of chemical carcinogen suppress malignant transformation of cultured cell

Fumiya Ogita, Akira Onodera, Asako Kashimura, Yasuo Tsutsumi, Norio It ...

Session ID: P-84
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4084.0

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HPV infection and lung cancer

Ya-Wen Cheng

Session ID: P-85
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4085.0

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p53 gene states are involved in the degree of bleomycin-induced cytotoxicity

Young Sook Lee, Seokjoo Yoon, Young-Su Yang, Jin Hwa Kim, Jeung-Hoon L ...

Session ID: P-86
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4086.0

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Cellular distributions of iron or copper-related molecules in the tumor promoting stage of a rat two-stage hepatocarcinogenesis model.

Sayaka Mizukami, Yuko Shimada, Ryohei Ichimura, Terumasa Suzuki, Sayak ...

Session ID: P-87
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4087.0

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Induction of apoptosis through the overaccumulation of p53 by cadmium

Maki Tokumoto, Yasuyuki Fujiwara, Tatsuya Hasegawa, Yoshiyuki Seko, Hi ...

Session ID: P-88
Published: 2009
Released on J-STAGE: July 17, 2009

DOIhttps://doi.org/10.14869/toxp.36.0.4088.0

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