We studied the abnormal rates of atherosclerosis risk factors attributable to overnutrition and marginal nutritional deficiency in schizophrenia inpatients. The hsCRP/Alb ratio, a predictor of mortality, is also composed of atherosclerosis risk factors. Since atherosclerosis risk factors that correlate with hsCRP/Alb ratio are high-risk factors related to mortality, these were examined for the subjects.
Among the risk factors for atherosclerosis attributable to overnutrition, obesity, and visceral adipose obesity had an abnormality rate of 50 % or more, while the high-risk factors for atherosclerosis correlated to hsCRP/Alb ratio were obesity, visceral adipose obesity, HDL-cholesterol, fasting plasma glucose, and HbA1c. Among atherosclerosis risk factors attributed to marginal nutritional deficiency, the abnormal rate for folic acid and zinc was over 50 % respectively. Histidine, threonine, and zinc were revealed to be high-risk factors for atherosclerosis correlated to hsCRP/Alb ratio. With the complication of obesity, branched-chain amino acids (Val, Leu, Ile) and methionine were also high-risk factors for atherosclerosis.
We concluded that schizophrenia inpatients would be in high mortality with high abnormal rates of atherosclerosis risk factors attributable to overnutrition and marginal nutritional deficiency.
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