The purpose of this study is to investigate some surfactants as root canal irrigants instead of sodium hypochlorite solution which cause the caustic action to periodontal tissue or oral mucosa. Test surfactants were cationic surfactants (CPC, CAB, benzalkonium chloride, benzethonium chloride), amphoteric surfactants (C14HSB), and non-ionic surfactants (E. 710, E. 715).
The minimum inhibitory concentration (MIC) of the surfactants against 20 anaerobic bacteria isolated from human infected root canals and 5 facultative bacteria and dissolving activity for type Ⅰ collagen gel were examined.
The results obtained were as follows :
The antibacterial effects of cationic and amphoteric surfactants were stronger than non-ionic surfactants. And growth of all bacteria tested were completely inhibited by 10-1% of cationic and amphoteric surfactants as same as 5% sodium hypochlorite solution.
The dissolving activities of cationic surfactants such as 10-1% cetyl trimethyl ammonium Bromide and 10-1% benzalkonium chloride were found as well as 5% NaOCl solution, however activities of amphoteric and non-ionic surfactants were less than half of 5% sodium hypochlorite solution.
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