著者らは, 1 歳6 カ月女児に発現した粘液嚢胞に遭遇し, 全摘出後, 経過観察を行ない,摘出物については神経組織学的検索を行なった。一般組織所見において,嚢胞壁は結合組織の軽度の増殖を伴う肉芽組織であり,導管の破裂ならびに一部に小嚢胞化を呈する所見が認められた。嚢胞内部には,粘液性物質,多数の形質細胞,マクロファージを貯留していた。これらの所見は,本症例がmucous extravasation typeであることを示していた。神経組織所見においては,粘液嚢胞成立との直接的因果関係は見出せなかったものの,変性に陥りながらも今だ好銀性を保っている神経線維が散見された。
以上の組織所見ならびに臨床所見について文献的考察を行なった結果,本症例の発生原因として,乳前歯の萌出に伴う慢性刺激が推察された。

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Mucoceles are known as so-called "mucous retention cyst" of minor salivary glands. Most of the lesions are located laterally on the lower lip but some in the midline. The clinical appearance is most commonly dome-shaped but rarely twin-peaked nodule. Our case is that of a 2-years-old boy who had twin-peaked mucoceles on the midline of the lower lip. The histlogical examination revealed that twin-peaked mucoceles were not lined by epithelium but by connective tissue, which were designated as the second pattern in Matuoka's (1972) classification.

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The objective of this study was to clarify the effect of CO₂ laser irradiation on oral tissue problemsin children, especially to treat mucocele. This study was carried out in the pedodontic clinic of Tokyo Medicaland Dental Hospital for 7 years between 1995 and 2001. A CO₂ laser was used on 29 subjects, of ages between0 to 15, having a mucocele on lip, lingual, or buccal mucosa. In each case, after administration of localanesthesia, the border of the mucocele was first incised around by a CO₂ laser in 3 or 4 watt continuous mode.Thereafter, the mass of the mucocele was completely removed away from the adjoining normal tissue, withoutbreaking its wall. No cases required suturing. The results were as follows: 1. A mucocele of lip or lingualmucosa, with a rich blood supply, was efficiently removed, without bleeding, giving a clear operative fieldduring the operation; 2. The surgery itself was simple and less time-consuming; 3. After two or three weeksthe wound was completely healed without almost any discomfort in all patients; 4. Wound contraction andscarring were decreased or eliminated; 5. Reoccurrence of a mucocele was not seen, except for one case of alingual mucocele. In conclusion the use of a CO₂ laser proved to be a very safe and effective mode for theremoval of mucocele, especially in small children.

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We succeeded in devising a new method for the surgical removal of mucoceles. This method is different from previous removal methods which use various impression materials for injection. An α-cyanoacrylate monomer adhesive is injected into the cystic cavity to coagulate (not to replace) its contents and cyst walls and remove them en bloc quite easily. Our surgical method is as follows:
An 18-gauge needle on a 2.5-cc syringe is inserted into the cyst, and some of the fluid within the cyst is aspirated. The syringe is then replaced with the one containing the α-cyanoacrylate monomer adhesive, and the adhesive is injected into the cyst. After the adhesive coagulates, the mass is easily removed as in the case of enucleation of a substantial benign tumor. Finally the wound is sutured.

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