Evans Blue (or Indigocarmin) was injected through celiac artery catheterization under the gastrofiberscopic observation, resulting in clearly demarcated gastric lesion from surrounding mucosa. We observed 33 lesions in 31 patients by this method, : 27 cases of gastric cancer, two gastritis, an atypical epitherium and a gastric ulcer. Method: Angiography was done by Seldinger's method. The Olympus gastrof iberscope was employed, the type is GTF-S2 or GTF-S3 and their light source using no filter. Following to the celiac angiography, the lesion of the stomach was photographed by conventional endoscopic method and 10ml. of 0.1w/v% Evans Blue (or 0.2w/v% Indigocarmin) was infused into the celiac artery within one second by assistant's hand injection, the lesion and the surrounding mucosa were taken by gastrofiberscopic camera until the dye fade out from the gastric mucosa. Result: By this new method, blood circuration at the vascular mesh of the gastric mucosa was observed through the injected dye movement, and the lesion was become easier and more accurate than conventional endoscopic photographs, i.e. irregular ulcer margin, conversing folds with clubbing, discoloration or coating mucosa, redness or bleeding and so on. In the lesion of well differentiated adenocarcinoma, the injected dye was better infused than anaplastic one. Conclusion: We believe that gastroendoscopic diagnosis by I.A.D. will make more useful diagnosis for various kinds of gastric lesions, especially in the differentiation between malignant and benign. As a future problem, the more accurate observation of the intra- and submucosal vascular mesh is expected to be possible by this method, and we hope that the I.A.D. would serve in detection of the extent of cancer spread which is covered by regenerated epitherium. Furthermore, the I.A.D. may enlage the diagnostic approach for the organs in the abdominal cavity under the laparoscopy.
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