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  • 小田切 孝人, 田代 眞人
    ウイルス
    2013年 63 巻 2 号 233-240
    発行日: 2013/12/25
    公開日: 2014/10/31
    ジャーナル フリー
  • Suguru TAKATSUTO, Kiyomi KOBAYASHI, Tsuyoshi WATANABE, Hiroki KURIYAMA, Tokuo FURUSE
    Agricultural and Biological Chemistry
    1988年 52 巻 12 号 3217-3218
    発行日: 1988年
    公開日: 2006/04/05
    ジャーナル フリー
  • Tsuyoshi WATANABE, Hiroki KURIYAMA, Tokuo FURUSE, Kiyomi KOBAYASHI, Suguru TAKATSUTO
    Agricultural and Biological Chemistry
    1988年 52 巻 8 号 2117-2118
    発行日: 1988年
    公開日: 2006/04/05
    ジャーナル フリー
  • Özkan ASLANTAŞ, Ebru Şebnem YILMAZ
    Journal of Veterinary Medical Science
    2017年 79 巻 6 号 1024-1030
    発行日: 2017年
    公開日: 2017/06/16
    [早期公開] 公開日: 2017/04/27
    ジャーナル フリー

    This study aimed to determine the prevalence of fecal carriage of extended spectrum β-lactamase (ESBL) and/or plasmidic AmpC β-lactamase (pAmpC) producing Escherichia coli among dogs (n=428) in Turkey. Polymerase chain reaction (PCR) and sequencing were used to characterize genes encoding β-lactamase and plasmid mediated quinolone resistance (PMQR). Antimicrobial susceptibility testing and PCRs for virulence genes and phylogenetic groups were also performed. Cefotaxime resistant

    E
    . coli isolates were detected in 95 (
    22
    .
    2
    %) of the swab samples. Sequencing analysis results showed occurrence of various β-lactamase genes: blaCTX-M-15 (62), blaTEM-
    1b
    (42), blaCMY-
    2
    (
    22
    ), blaCTX-M-
    3
    (16), blaCTX-M-1 (15), blaOXA-1 (
    9
    ) and blaSHV-12 (
    3
    ) alone or in combination. The most frequently encountered phylogenetic group was group A1 (35.
    8
    %), followed by group
    D2
    (
    22
    .1%),
    B
    1 (15.
    8
    %),
    D1
    (
    9
    .
    5
    %), A0 (7.4%),
    B22
    (
    5
    .
    3
    %) and
    B23
    (4.
    2
    %), respectively. PMQR genes, aac(
    6
    ’)-Ib-cr, qnr
    S1 and qnrB10 were detected in 25.
    3
    , 10.
    5
    and 1.1% of the isolates, respectively. While all isolates were susceptible to imipenem and amikacin, resistance rates to non-β-lactam antibiotics ranged from 20.0% for tobramycin to 56.
    8
    % for tetracycline. The virulence genes were only detected in 34 (36.
    2
    %) of the isolates and this isolates carried single or various combination of virulence genes of iucD, papC, papE,
    f17a
    -A and eaeA. Four isolates were identified as human virulent pandemic CTX-M-15 producing
    E
    . coli
    clone O25
    b
    :ST131/
    B
    2
    . To the best of our knowledge, this is the first study to show fecal carriage of ESBL/pAmpC type β-lactamase producing
    E
    . coli
    isolates among dogs in Turkey.

  • George W. Lee
    燃料協会誌
    1973年 52 巻 3 号 171-177
    発行日: 1973/03/20
    公開日: 2010/06/28
    ジャーナル フリー
  • T BAKER, C. RANGACHARYULU
    日本物理学会講演概要集
    1999年 54.2.1 巻 23pSM-6
    発行日: 1999/09/13
    公開日: 2018/03/04
    会議録・要旨集 フリー
  • CHANIDNUN POTHIRAKSANON, DENNES T. BERGADO, HOSSAM M. ABUEL-NAGA
    SOILS AND FOUNDATIONS
    2010年 50 巻 5 号 599-608
    発行日: 2010年
    公開日: 2010/12/28
    ジャーナル フリー
    In this study the field feasibility of an innovative thermal technique to improve the performance of prefabricated vertical drains (PVD) used in conjunction with the preloading ground improvement method is investigated. For this purpose, two identical
    6
    .0 m high full-scale test embankments for preloading were constructed over the soft Bangkok clay where a conventional PVD system was installed underneath one embankment and a novel prefabricated vertical thermo-drain (PVTD) system was utilized for the other. The PVTD unit consists of a U-tube made of cross-linked polyethylene plastic (PEX) that is attached to a conventional PVD unit. Preheated water at about
    90
    °C is circulated through the attached U-tube to raise the soil temperature underneath the PVTD embankment. The behavior of the two test embankments were compared in terms of excess pore water pressure and consolidation results. The comparison shows the advantage of a PVTD system over a conventional PVD system. The rate of consolidation increases significantly in the PVTD system due to the temperature effect on the hydraulic conductivity. Moreover, the embankment with the PVTD system generates more settlement due to the thermally induced irreversible contraction of saturated normally consolidated soft Bangkok clay.
  • R.G. WAN, P.J. GUO
    地盤工学会論文報告集
    1999年 39 巻 6 号 1-11
    発行日: 1999/12/15
    公開日: 2008/02/29
    ジャーナル フリー
    This paper outlines a mathematical description of the stress dilatancy behaviour of granular materials which accounts for stress level and void ratio dependencies. The consideration of these aspects has important implications in the modelling of granular material behaviour. In fact, granular material mechanical response is largely dominated by the evolution of dilatancy, fabric and void ratio histories. The starting point in this study is the well established Rowe's theory which is revisited and ultimately modified by introducing a factor linked to governing state parameters in order to describe the complete behaviour of granular materials during deformation. Numerical simulations of triaxial tests on granular materials at different void ratios and stress levels are herein presented to illustrate the model.
  • 山本 雅史, Abkenar Asad Asadi, 松本 亮司, 根角 博久, 吉田 俊雄, 國賀 武, 久保 達也, 冨永 茂人
    園芸学会雑誌
    2007年 76 巻 1 号 36-40
    発行日: 2007年
    公開日: 2007/03/06
    ジャーナル フリー
    カンキツ主要12種を用いて染色体のクロモマイシン
    A3
    (CMA) 染色を行った.染色体は CMA(+) バンドの有無および位置から 7 種類に区分できた.すなわち,CMA(+) を A: 両端および動原体近傍に有する,
    B
    : 一方の端部と動原体近傍に有する,C: 両端に有する,
    D
    : 一方の端部に有する,
    E
    : CMA(+) がない,
    F
    : 動原体近傍に有する,Dst: 付随染色体を有する
    D
    型,である.各種はこれらのうち
    2
    6
    種類の染色体を有し,独自の CMA バンドパターンを示した.C. medica では
    2
    B
    +
    8
    D
    +
    8
    E
    C. limon では 1
    B
    + 1C +
    8
    D
    +
    8
    E
    C. aurantifolia では
    2
    B
    +
    9
    D
    + 7
    E
    C. aurantium では 1A + 1
    B
    + 1C + 7
    D
    +
    8
    E
    C. sinensis では
    2
    B
    +
    2
    C + 7
    D
    + 7
    E
    C. maxima では
    3
    A +
    3
    C + 4
    D
    +
    8
    E
    C. paradisi では
    2
    A +
    3
    C +
    6
    D
    + 7
    E
    C. ichangensis では
    2
    B
    +
    2
    C + 12
    D
    +
    2
    E
    C. latipes では
    2
    A +
    5
    C +
    8
    D
    +
    3
    E
    C. micrantha では 1
    B
    + 11
    D
    + 4
    E
    +
    2
    Dst,C. macroptera では
    2
    B
    + 1C + 11
    D
    +
    3
    E
    + 1
    F
    C. hystrix では
    3
    B
    + 1C +
    8
    D
    +
    3
    E
    +
    2
    F
    + 1Dst であった.
  • Grover Loening
    日本航空学会誌
    1963年 11 巻 119 号 373-380
    発行日: 1963年
    公開日: 2009/05/25
    ジャーナル フリー
  • / 鵜飼 恵三, KEIZO UGAI
    地盤工学会論文報告集
    1998年 38 巻 3 号 201-207
    発行日: 1998/09/15
    公開日: 2008/02/29
    ジャーナル フリー
    A comparative study of the static and dynamic response of a slope is carried out, using the large deformation theory of the updated Lagrangian formulation and the conventional infinitesimal theory. In the static analysis, a strength reduction method proposed by one of the authors is used to evaluate the safety factor of the slope. It is found that by the large deformation theory, the safety factor is larger than that calculated by the infinitesimal theory, and this difference becomes large along with the reduction of elastic modulus. In the dynamic analysis, it is observed that the large deformation theory gives smaller sliding displacement and larger response acceleration than the infinitesimal approach. It is concluded that in many cases the large deformation approach gives more adequate solutions.
  • 佐藤 敬之輔
    デザイン学研究
    1970年 1970 巻 11 号 45-55
    発行日: 1970/03/30
    公開日: 2017/07/25
    ジャーナル フリー
    [1] The purpose of this reserch is to make clear what type of design can give good effects to win the high readership score. At the begining I had to know what factors decide the readership score, and how to change the quality of the desing into numerical value. I have used the method of multi-dimentional analysis with the help of a computer, and got the estimation formula, with 7 kinds of factors, as follows ; A^^〜=
    B
    +C+
    D
    +K+aE+bF+cG. A^^〜=estimated values of the readership score. 1)
    B
    , C,
    D
    , K : these four factors are given as category values (so we call them); each factor is classified into several categories.
    B
    =week day, classified into 7 categories. C=pages of a newspaper, which are characterized by the kinds of articles, news, and the other reading matters, classified into
    22
    categories.
    D
    =kinds of goods and trades of the advertizement, classified into 14 catedories. K=constants, given to each 13 surveys.
    2
    )
    E
    ,
    F
    , G : these factors are given as numerical values. G=area of advertizement, measured by the unit of column in the whole page length, being classified into
    6
    kinds of area (
    2
    .
    5
    ,
    3
    .
    5
    ,
    5
    , 7, 10, 15) and 15 column means a whole page, about
    2
    ,000cm^
    2
    .
    E
    ,
    F
    are the marks obtained in the design of advertizements.
    E
    =sum of the marks obtained in each design element on the advertizement.
    F
    =the marks obtained on the whole effect of the design.
    3
    ) a,
    b
    , c : coefficients Using the above formula with the category values and the coefficients, we can obtain the naked design effect from the actual value A of readership score: aE+bF=A-(
    B
    +C+
    D
    +K+cG). In this research, I used 1,829 data of readership score from 1960 to 1968, being obtained by 13 survevs, spring and autumn twice a year. The sample of size each survey was
    3
    ,541,
    2
    ,251, or 200 in the other 11 surveys. Multiple correlation coefficient between the estimated value A^^〜 and the actual value A is 0.951. The table
    2
    ^* shows the contribution indexes of each factor by
    3
    kinds of expression-(1) Range : the absolute difference between the maximum and the minimum category values, (
    2
    ) Standard deviations of the category values, (
    3
    ) Partial correlation coefficient : the relationship between the actual values A and each factors. *see the table
    2
    in the thesis in Japanese. [
    2
    ] The important point was in the determination of the values of
    E
    ,
    F
    .
    E
    is the sum of the marks obtained in each design element, classified into four kinds :
    E
    =
    E
    _1+
    E
    _
    2
    +
    E
    _
    3
    +
    E
    _4. design elements [table]
    E
    _1,
    E
    _
    2
    ,
    E
    _
    3
    ,
    E
    _4, these values have the
    5
    grades, as 0, 1,
    2
    ,
    3
    , 4 and 0 is given to the design that has no attractive effect or no applicable element. And
    E
    obtain the marks of 0 to
    9
    grades as the sum of them. The values of
    F
    have also
    5
    grades, 0 to 4. The principles to determine the values of
    E
    ,
    F
    are as follows : a) The marks obtained of
    E
    ,
    F
    must be the relative values among the each survey, and at the same time, they must have constancy within the same survey-the same elements of design must win the same marks obtained.
    b
    ) They must be determined as to win the highest multiple correlation coefficient, when they are put into the estimation formula. c) They must be reasonable. In order to justify them, we must carry many researches on the actual condition. The frequency of accurence of each grade of
    E
    ,
    F
    values, as the table
    5
    -4, and
    5
    -
    5
    in the thesis in Japanese.
  • 藤井 澄三, 斎藤 徹, 木津 京子, 林原 央美, 熊澤 幸成, 中嶋 悟視, 藤澤 哲則
    Chemical and Pharmaceutical Bulletin
    1991年 39 巻 2 号 301-308
    発行日: 1991/02/25
    公開日: 2008/03/31
    ジャーナル フリー
    A detailed account is given of the syntheses of
    9
    -alkyl-
    2
    -deuterioadenines (
    5
    b
    -
    d
    ), adenosine-
    2
    -
    d
    (
    5
    e
    ), and
    2
    '-deoxyadenosine-
    2
    -
    d
    (
    5
    f
    ) from the
    9
    -substituted adenines 1
    b
    -
    f
    through cyclization of the aminoimidazolecarbox-amidine salts
    9
    or the corresponding free bases
    8
    with formic-
    d
    acid-
    d
    or 1-(formyl-
    d
    )-
    2
    (1H)-pyridone. Glycosidic hydrolysis of
    5
    e
    with boiling 0.
    5
    N aqueous HCl afforded adenine-
    2
    -
    d
    (
    5
    a) in 77% yield. Peracid oxidation of
    5
    a-
    e
    produced the corresponding 1-N-oxides (12a-
    e
    ) in fair yields. Methylation of
    9
    -methyl- (12
    b
    ) and
    9
    -benzyladenine-
    2
    -
    d
    1-oxide (12
    d
    ) and adenosine-
    2
    -
    d
    1-oxide (12
    e
    ) with MeI in
    AcNMe2
    gave the corresponding 1-methoxy derivatives (13
    b
    ,
    d
    ,
    e
    ) in good yields. Dimroth rearrangements of 13
    b
    , 13
    d
    , and 13
    e
    via the free bases 14
    b
    , 14
    d
    , and 14
    e
    furnished the
    N6
    -methoxy isomers 15
    b
    , 15
    d
    , and 15
    e
    , but their isotopic purities were unsatisfactory. Unambiguous assignments of the purine-ring proton signals in the proton nuclear magnetic resonance spectra of the unlabeled adenines (1a-
    f
    ,
    2
    a-
    e
    ,
    3
    b
    ,
    d
    , and 10
    e
    ) have been made by comparison with those of the labeled species (
    5
    a-
    f
    , 12a-
    e
    , 13
    b
    ,
    d
    , and 14
    e
    ).
  • 末次 康将
    マリンエンジニアリング
    2021年 56 巻 5 号 680-687
    発行日: 2021/09/01
    公開日: 2021/10/12
    ジャーナル フリー
  • 安福 規之, / 大嶺 聖, 落合 英俊, HIDETOSHI OCHIAI
    地盤工学会論文報告集
    2001年 41 巻 3 号 17-30
    発行日: 2001/06/15
    公開日: 2008/02/29
    ジャーナル フリー
    The present paper aims at developing a simplified model for a stress-strain relationship at small strains up to an initial yielding of homogeneous saturated frozen sand. The modelling of elastic moduli for an ice-sand mixture as a composite geomaterial is first introduced based on previous studies, where a saturated frozen sand is treated as the icesand mixture. The applicability of modelling the elastic moduli under constant temperature is then discussed from the theoretical and experimental points of view. In addition, the hyperbolic stress-strain modelling of saturated frozen sand at small strain is presented. The effect of the volume fraction of sand, stiffness of sand inclusion and temperature changes on the elastic moduli and the stress-strain behaviour up to about 1-
    2
    % axial strain, which is defined as an upper yield stress, are investigated through the model, whose applicability is verified in comparison with the experimental data.
  • 伊東 常男, 富井 保雄, 内藤 貴之, 山村 美奈子, 石川 一郎, 川原 徳夫, 水野 義久, 小倉 治夫
    Chemical and Pharmaceutical Bulletin
    1989年 37 巻 8 号 2197-2199
    発行日: 1989/08/25
    公開日: 2008/03/31
    ジャーナル フリー
    5
    -Amino-
    6
    -mercapto-1,
    3
    -dimethyluracil (
    2
    ) was prepared by the treatment of
    5
    ,
    6
    -diamino-1,
    3
    -dimethyluracil (1) with liquid
    H2S
    and pyridine in a sealed steel tube at 60°C for 20 h. Thiazolo[
    5
    , 4-
    d
    ]pyrimidinediones
    3
    a,
    b
    were obtained from
    2
    by cyclization with
    HCO2H
    and AcOH.Under stringent conditions, however, 1 was converted into the
    5
    ,
    9
    -dihydrodipyrimido[4,
    5
    -
    b
    :
    5
    ', 4'-
    e
    ][1, 4]thiazine derivtive 4a.The structure of 4a was confirmed by spectral (nuclear magnetic resonance and mass spectra) data and by comparison with a sample which was prepared from
    2
    and
    5
    -hydroxy-1,
    3
    -dimethyluracil.Benzylation of 4a gave 1,
    3
    , 7,
    9
    -tetramethyl-
    5
    -benzyl (or p-bromobenzyl)-
    5
    ,
    9
    -dihydrodipyrimido[4,
    5
    -
    b
    :
    5
    ', 4'-
    e
    ][1, 4]thiazine-
    2
    , 4,
    6
    ,
    8
    -(1H,
    3
    H, 7H)-tetrone (4
    b
    , c) and 1,
    3
    , 7,
    9
    -tetramethyl-
    5
    -benzyl (or p-bromobenzyl)-
    5
    ,
    9
    -dihydropyrrolo[
    3
    ,
    2
    -
    d
    : 4,
    5
    -
    d
    ']dipyrimidine-
    2
    , 4,
    6
    ,
    8
    -(1H,
    3
    H, 7H)-tetrone (
    6
    a,
    b
    ).
  • R. CARDOSO,
    E
    .
    E
    . ALONSO
    SOILS AND FOUNDATIONS
    2009年 49 巻 3 号 315-327
    発行日: 2009年
    公開日: 2011/01/27
    ジャーナル フリー
    Embankments made with marl and other soft clayey rocks result in an agglomerated structure of finite size particles. These particles evolve however, resulting in major changes of the overall behaviour of the aggregate. The development of settlements and the loss of strength in time are the main concerns in practice. The mechanisms leading to the breakage and eventually the destructuration of one single rock particle are investigated using the concepts of unsaturated soil mechanics since wetting and drying cycles, controlled by atmospheric changes, result in strong suction changes and are one of the main reasons for rock degradation. Numerical simulations of the behaviour of individual rock fragments when wetted until full saturation were performed. Several contributing factors, namely suction change rate, initial suction and confinement were investigated. The knowledge learned with the simulation of the degradation of single rock fragments was extended to simulate the behaviour of particle arrangements under some representative stress and suction paths. Some results of suction controlled tests used for the calibration of the models are presented. The calculated behaviour of single particles and aggregates under wetting is discussed and qualitatively compared with experimental observations of the individual rock fragments and the compacted material. The results obtained provide a new insight into the nature of degradation induced by wetting and drying. They provide also a mechanical explanation, at the level of rock fragments, for the overall behaviour of aggregates.
  • 香山 滉一郎, 森下 政夫, 張 国鋒
    粉体および粉末冶金
    2006年 53 巻 5 号 419-429
    発行日: 2006年
    公開日: 2006/12/19
    ジャーナル オープンアクセス
    The phase diagrams of the Ni-Mo-
    B
    and Ni-W-
    B
    ternary systems in the region of less than 50mol%
    B
    were constructed by thermodynamic calculation, based on the data obtained by thermodynamic measurement of the related materials. We found three ternary eutectic points and three or two ternary peritecto-eutectic points as follows:
    E1
    :L (1365K, 71.
    5
    mol%Ni-
    6
    .0mol%Mo-
    22
    .
    5
    mol%
    B
    )=(Ni)+
    Ni3B
    +
    NiMo2B2

    E2
    :L (1355K, 62.
    5
    mol%Ni-
    2
    .
    5
    mol%Mo-30.
    5
    mol%
    B
    )=
    Ni3B
    +
    Ni2B
    +
    NiMo2B2

    E3
    :L (1445K, 42.0mol%Ni-30.
    6
    mol%Mo-10.
    3
    mol%
    B
    )=(Ni)+NiMo+
    NiMo2B2

    P1:L (1812K, 34.
    9
    mol%Ni-42.
    3
    mol%Mo-
    22
    .
    8
    mol%
    B
    )+MoB=
    Mo2B
    +
    NiMo2B2

    P2
    :L (1633K, 42.
    3
    mol%Ni-40.4mol%Mo-17.
    3
    mol%
    B
    )+Mo=
    Mo2B
    +
    NiMo2B2

    P3
    :L (1812K, 53.
    5
    mol%Ni-33.7mol%Mo-12.
    8
    mol%
    B
    )+Mo=NiMo+
    NiMo2B2

    E1
    :L (1622K, 51.0mol%Ni-31.
    6
    mol%W-17.4mol%
    B
    )=(Ni)+W+
    NiW2B2

    E2
    :L (1260K, 71.0mol%Ni-7.0mol%W-
    22
    .0mol%
    B
    )=(Ni)+
    Ni3B
    +
    NiW2B2

    E3
    :L (1291K, 65.4mol%Ni-4.
    8
    mol%W-29.
    8
    mol%
    B
    )=
    Ni2B
    +
    Ni3B
    +
    NiW2B2

    P1:L (2115K, 23.
    8
    mol%Ni-43.1mol%W-33.1mol%
    B
    )+WB=
    W2B
    +
    NiW2B2

    P2
    :L (1657K, 48.
    9
    mol%Ni-33.1mol%W-18.0mol%
    B
    )+
    W2B
    =W+
    NiW2B2

    The calculated phase diagrams are expected to be useful for the development of new Ni-based heat-, corrosion- or wear-resistance alloys.
  • 張 建民, 社本 康広, 時松 孝次
    地盤工学会論文報告集
    1998年 38 巻 2 号 143-163
    発行日: 1998/06/15
    公開日: 2008/02/29
    ジャーナル フリー
    Based on the concept "intermediate soil wedge" which is dependent on mobilized frictional resistance, a new theory has been developed for evaluating the seismic earth pressures against retaining walls under any condition between the active and passive states. For this theory, the seismic earth pressure is separated into four components according to their formation. New equations are proposed to determine the distribution, resultant and point of application for each component. An equivalent seismic coefficient is introduced to take into account non-uniform seismic acceleration distribution with depth. The equations place special emphasis on dependence of the seismic earth pressure on mode and level of wall movement. The equations can be reduced to the Mononobe-Okabe equation for the limiting conditions. Their applicability was confirmed by comparing the predictions with a number of previous model test results.
  • RAJ SIDDHARTHAN, GARY M. NORRlS
    土質工学会論文報告集
    1991年 31 巻 2 号 51-64
    発行日: 1991/06/15
    公開日: 2008/02/29
    ジャーナル フリー
    A finite element model capable of taking into account nonlinear hysteretic soil behavior is presented to study earthquake induced retaining wall movement. The model also accounts for increase in lateral stresses and settlement associated with grain slip caused by cyclic loads. The predictive capability of the proposed method is verified by comparing responses given by the model with those computed by another existing finite element model and also with responses recorded at the Cambridge centrifuge facility. The study reveals that the wall displacement can be substantially affected, among other factors, by the increase in lateral stresses due to grain slip and wall-soil friction. Care should be taken when selecting a constant value of wall-soil friction angle for the entire duration of excitation since structural changes can occur in the soil adjacent to the wall.
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