11-Amino-6, 6a, 7,
8
,
9
, 10, 10a, 11-octahydrodibebenzo[
b
,
e
]thiepines (6a-d) and -oxepines (7a-d) were synthesized by the Leuckart reaction of 6, 6a, 7,
8
,
9
, 10, 10a, 11-octahydro-11-oxodibenzo[
b
,
e
]thiepines (
1
a,
b
)and -oxepines (2a,
b
) followed by hydrolysis of the reaction products 4a-d and
5
a-d, respectively. The four diastereomers, cis(6a-H, 10a-H)-cis(10a-H, 11-H) 6a and 7a, cis(6a-H, 10a-H)-trans(10a-H, 11-H) 6
b
and 7
b
, trans(6a-H, 10a-H)-trans(10a-H, 11a-H)6c and 7c, and trans(6a-H, 10a-H)-cis(10a-H, 11-H) 6d and 7d, were isolated and their configurations and conformations were elucidated by chemical methods together with
1H
-nuclear magnetic resonance spectroscopic and X-ray crystallographic analyses.
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