2000 Volume 48 Issue 8 Pages 1239-1241
After anaerobic incubation of abrusin 2"-O-β-D-apioside (1) with a human fecal suspension, five metabolites were isolated and identified as abrusin (2), 1-(2', 6'-dihydroxy-3', 4'-dimethoxyphenyl)-3-(4"-hydroxyphenyl)-propan-1-one (5), 5, 6-dimethoxybenzene-1, 3-diol (6), 3-(4'-hydroxyphenyl)propionic acid (7) and 3-phenylpropionic acid (8). However, methyl ether derivatives of abrusin (4'-O-methylabrusin and 4'-O-, 5-O-dimethylabrusin) resisted degradation under the same conditions.