Inhibitors of Xanthine Oxidase from Alpinia galanga

TADATAKA NORO; TAKESHI SEKIYA; MASAKO KATOH(nee ABE); YASUSHI ODA; TOSHIO MIYASE; MASANORI KUROYANAGI; AKIRA UENO; SEIGO FUKUSHIMA

doi:10.1248/cpb.36.244

TADATAKA NORO, TAKESHI SEKIYA, MASAKO KATOH(nee ABE), YASUSHI ODA, TOSHIO MIYASE, MASANORI KUROYANAGI, AKIRA UENO, SEIGO FUKUSHIMA

Author information

Keywords: 1'-acetoxychavicol diacetate phenylpropenol

JOURNAL FREE ACCESS

1988 Volume 36 Issue 1 Pages 244-248

DOI https://doi.org/10.1248/cpb.36.244

Details

Abstract

Xanthine oxidase (XO) inhibitors were isolated from the rhizomes of Alpinia galanga (Zingiberaceae), and were identified as trans-p-coumaryl diacetate (1), trans-coniferyl diacetate (2), [1'S]-1'-acetoxychavicol acetate (3), [1'S]-1'-acetoxyeugenol acetate (4) and 4-hydroxybenzaldehyde (5). The type of inhibition by either 1 or 3 with respect to xanthine as a substrate was uncompetitive.

Corresponding author

Register with J-STAGE for free!