Changes of Immunological Response after Experimentally Ozonated Autohemoadministration in Calves

Nobuhiro TERASAKI; Atsuya OGATA; Hiromichi OHTSUKA; Keiji TAMURA; Fumio HOSHI; Masateru KOIWA; Seiichi KAWAMURA

doi:10.1292/jvms.63.1327

Nobuhiro TERASAKI, Atsuya OGATA, Hiromichi OHTSUKA, Keiji TAMURA, Fumio HOSHI, Masateru KOIWA, Seiichi KAWAMURA

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Keywords: calf, immunological response, ozonated autohemoadministration

JOURNAL FREE ACCESS

2001 Volume 63 Issue 12 Pages 1327-1330

DOI https://doi.org/10.1292/jvms.63.1327

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Abstract

Changes in subsets of peripheral blood mononuclear cells and lymphocyte blastogenesis reaction were observed after ozonated autohemoadministration (OAHA) in calves. Ten healthy calves were used in this study. After OAHA, CD8⁺ cells, CD14⁺ cells and WC1⁺cells increased (p<0.05). The level of lymphocyte blastogenesis stimulated by PHA decreased after OAHA. A significant increase in serum IL-6 activity was observed in OAHA calves. These results suggested that OAHA induced immunological changes in calves.

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