ポリリジンによる微生物制御技術

抄録

A purpose of this treatise is introduction of ε-Poly-L-lysine（ ε-polylysine）, which is homo polymer of L-lysine.

It is produced by fermentation method in aerobic culture with Streptomyces albulus. Chemical structure

of ε-polylysine is too unique, it is polymerized ε-position amino group and α-position carboxyl group in Llysine

by amide bond, that structure resembles nylon 6. α-Position amino groups in ε-polylysine charges with

a cationic charge in water under pH 9, it behaves as a cationic polymer. This cationic charge provides variety

of effect, such as antimicrobial effect, adsorption or dispersion effect for electric charged components, and so

on.

ε-Polylysine has been approved as a natural origin food preservative in Japan since 1989, also has been approved

in south Korea, the United States, and China. In addition, it is used as not only food preservative but

also as an ingredient for cosmetics and chemicals.

ε-Polylysine inhibit various microorganisms at low concentration, and it provides synergistic effect with other

antimicrobial agents, such as alcohol, organic acids, chelating agents, and so on. Recently, it has found out

that combination of ε-polylysine and natto-extract（ NAP） provides inhibition effect of Feline calicivirus（ FCV）