抄録
Cholinesterase staining and Gomori's trichrome staining were performed in serial sections of soleus muscles of rats daily administered with 0.625mg/kg neostigmine for 2 or 3 weeks. In the affected muscle fibers, abnormally expanded subsarcolemmal sarcoplasmic masses were frequently observed with a homogenous greenish blue appearance by Gomori's trichrome staining. Cholinesterase activities were clearly demonstrated in serial sections at the areas corresponding to these sarcoplasmic masses.
In teased fibers of the affected muscles, the areas adjacent to cholinesterase activities appeared enlarged and expanded.
It is evident that there exists a close relationship between the sarcoplasmic mass and the motor endplate histochemically.
