Abstract
Distribution of radioactive carbon in tissues from mice injected in vivo with [1-14C]-2-deoxyglucose was studied by whole-body autoradiography of 6% cold perchloric acid treated sections and untreated sections. The results clearly showed that there were certain tissues and organs in which significant amounts of radioactive carbon from [1-14C]-2-deoxyglucose were incorporated into acid-insoluble substances. They were muscular tissues, such as the diaphragm, skeletal muscle, myocardium and small and large intestinal muscles. This suggests that the metabolic system for 2-deoxyglucose is different in various tissues and organs.
