抄録
Several reports have been appeared as to the production site of human prolactin (PRL) during pregnancy. They are grossly divided into two groups of opinions or proposals, i. e. placental tissue and hypertrophy and/or hyperplasia of pituitary lactotrophs triggered by elevated estrogen in plasma. This difference may be caused by the different pattern of PRL concentration in either plasma or amniotic fluid. Among opinions to support placental synthesis, the decidual role seems to be dominant.
In this study, the authors describe syncytial synthesis of PRL in the placental tissue at term by a method of fluorescent antibody technique. Decidual tissue is concerned not with synthesis but deposition of PRL which is produced in tissue otherwise decidua.