抄録
Succinic dehydrogenase activity of the 15 to 20 day murine (CD-1) mandibular joint was determined by incubating cryostat sections at 37°C for one hr in a medium containing sodium succinate. A series of adjacent sections were incubated in a medium from which the substrate had been deleted. The SDH activity in the mandibular joints of 15 and 16 day embryos was minimal and thereafter a gradual increase in the enzyme activity was evident. The cells involved in intercellular matrix elaboration (chondroblasts and osteoblasts) and those concerned in remodeling of existing structures (osteoclasts/chondroclasts) demonstrated high levels of enzyme activity. The activity observed in chondrocytes varied between slight and moderate, however, the osteocytes were non-reactive. Intense SDH activity was observed in the medial and lateral pterygoid muscles as well as in the trigeminal ganglia.