DNA CYTOFLUOROMETRY OF BONE AND SOFT PART TUMORS

Abstract

A cytofluorometric evaluation of the DNA content of the bone and soft part tumor cell nuclei was undertaken in 14 cases of benign tumors and 28 cases of malignant tumors. In benign tumors, the DNA values were in the diploidtetraploid range and there were no tumor cells which had more DNA value than the octaploid. On the contrary, malignant tumors were characterized by the prevalence of polyploid cells.
The study suggests that DNA cytofluorometry is useful for differentiating between malignant and benign tumors in the bone and soft part tissues.