Abstract
A calcium-binding protein, calmodulin is thought to be an intracellular mediator for many calcium-dependent processes. In this report, to see the immunohistochemical localization of calmodulin in human tissues, routine paraffin sections were studied using either indirect immunoperoxidase or immunofluorescent method, and the characteristic staining was observed in some types of the epithelial cells, the neurons and others. After the preservation of the tissues in the formalin and in the paraffin sections, the immunoreactivity of calmodulin could still be demonstrated, which allows the accumulation of the knowledge concerning the pathological as well as normal distribution of calmodulin in human tissues for the elucidation of calmodulin functions in the human body.
