Abstract
The distribution of binding sites of two tritiated lectins, Concanavalin A (Con A) and wheat germ agglutinin (WGA), has been examined in mice by means of in vitro whole-body autoradiography, which is a powerful technique for localization of radioactive substances and enzymes in organs. Tritiated Con A exhibited a widespread distribution of binding sites in organs of the mouse. Tritiated Con A strongly bound to the stomach, rectum, cartilage and contents of the epididymis and deferent duct of all the organs tested. Tritiated WGA showed a restricted distribution of binding sites. Tritiated WGA vividly bound to the colon, cartilage and seminal vesicle of all the organs tested. In general, the present results are consistent with those obtained previously by microscopical studies.
