Abstract
Immunohistochemical identification of keratin proteins in ductal segments was reported in salivary glands of the hamster, guinea pig, dog, horse, pig, cow, goat, monkey and human. The keratin found in salivary gland ducts was usually located in the luminal cytoplasms of the striated duct (SD) epithelium in comparatively high concentrations. The luminal cytoplasm of intercalated duct (ICD) cells also displayed a high level of keratin staining. The excretory duct (ED) cells were positive for keratin in the inner side cytoplasm of the epithelium. The SD epithelium of the guinea pig submandibular gland was characterized by the presence of negative or positive keratin staining. The cells in the outer layer of large EDs in mammals salivary glands disclosed the highest degree of keratin staining.