IMMUNOCYTOCHEMICAL LOCALIZATION OF GLUTATHIONE-PEROXIDASE (GSH-PO) IN THE RAT OVARY

Abstract

Immunocytochemical localization of glutathione-peroxidase (GSH-PO) in the rat ovary was studied. In ovaries, GSH-PO was clearly detected in granulosa cells of large follicles taken from 2300hr of proestrus to 0500hr of estrus as well as lutein cells taken from midnight of diestrus I to morning of diestrus II. There is a strong correlation between elevated progesterone levels in plasma and immunocytochemical localization of GSH-PO in rat ovarian tissues including granulosa cells and lutein cells. Based on our data, the possible roles of GSH-PO in ovarian tissues were discussed.