DISTRIBUTION OF CATHEPSIN L IN RAT BRAIN AS REVEALED BY IMMUNOHISTOCHEMISTRY

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Immunohistochemically detectable cathepsin L was demonstrated in rat brain by means of a monospecific, polyclonal antiserum. Sternberger's unlabeled immunoenzyme technique was employed. Cathepsin L immunoreactive material was found in multiple hypothalamic and brain stem neurocytes as well as in some hippocampal and neocortical nerve cells. Cathepsin L was also detected in ependymal cells of the plexus choroideus.