抄録
The present study deals with the effects of Urea, Nirma, DDT and Malathion in combination on 5′-nucleotidase activity in the liver, kidney intestine and gills of a fresh water teleost Heteropneustes fossilis at sublethal levels after short term and long term exposure. Marked alteration in 5′-nucleotidase activity were noted at most of the concentrations. Significant stimulation of enzyme activity was observed in the kindey. In the gills a notable synergistic effect was the presence of dense deposits of 5′-nucleotidase reaction product in the pillar cells of alternate gill lamina in the treated specimens. The most remarkable feature observed was that the enzyme leaves the area of operation by leaving the membrane system of its anchorage subsequent to the treatment of above mentioned contaminants and pollutants.
