1992 年 25 巻 1-2 号 p. 3-8
Activity of guanylate cyclase (GC) in the rat hippocampus was studied cytochemically and biochemically. Histochemical activation of the enzyme could be reliably demonstrated only with nitroprusside and nitroglycerin. For the histochemical demonstration of GC activity the cerium precipitation technique was used. The enzyme was localized in small and medium-sized neurons and astroglial cells. Intensely stained were postsynaptic densities and glial cell processes. Surrounding capillaries the reaction was restricted to microvascular glial cell processes and basement membrane.