PHENOTYPIC AND GENOTYPIC IDENTIFICATION OF HUMAN LYMPHOCYTES AND THEIR APPLICATION FOR DISEASES
1992 年 25 巻 5 号 p. 539-545
詳細
1992 年 25 巻 5 号 p. 539-545
Lymphocytes are called “nature's best known cells”, since their function has been studied in detail by many aggressive immunologists and their surface phenotypes have been investigated thoroughly with the monoclonal antibodies (MAbs) to surface antigens of lymphocytes. In addition, a surprisingly rapid progress of gene engineering, including that of immunoglobulin and T cell receptor has been used for the investigation of lymphocyte genotypes. This knowledge was directly applied for the analysis and diagnosis of lymphoid diseases.
