This study is an attempt to consider the architectural design of the ‘WHO Headquarters’ in the ‘International Organization District’, Geneva, by analyzing the 15 proposals for competition and the realized building by Jean Tschumi. We examine the relationship between the site’s surrounding environment and the three-dimensional composition of each buildings. It was revealed that the upper part of the buildings faced toward ‘Palais des Nations’ and the lower part of the buildings is shaped to the microtopography of the site. The panoramic landscape specific to Lake Geneva is limited horizontally on the ground floor connecting them.