Full scale loading test up to large story drift on Exterior Wall of ALC panel with window and door attached to steel moment frame was conducted. No damage was observed on the surface without openings except for the bottom of the panel. On the surface with openings, many damages such as cracks in the panel and breaks in the welding of the substrate were observed especially at large story drift angle of 1/50 or more. In addition, degrading of the openablility of the window and door according to residual story drift angle were examined.