The Japanese Journal of Antibiotics
Online ISSN : 2186-5477
Print ISSN : 0368-2781
ISSN-L : 0368-2781
ANTIMICROBIAL ACTIVITY OF AO-128, A NOVEL INHIBITOR OF α-D-GLUCOSIDASE, AGAINST ANAEROBIC BACTERIA
NAOKI KATOKUNITOMO WATANABEKAZUE UENO
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1992 年 45 巻 10 号 p. 1267-1269

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The in vitro antimicrobial activity of AO-128, an inhibitor of α-D-glucosidase, was evaluated against anaerobic bacteria of 45 reference strains (12 genera, 44 species). AO-128inhibited no strains tested at a concentration of1, 600μg/ml. The results strongly suggested that this compound would not have any influence on the human intestinal microflora, a majority of which is composed of anaerobic bacteria.

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