1960 年 13 巻 5 号 p. 327-334
An orange rod crystalline antibiotic pigment having acid-base-indicating property has been isolated from the culture of a strain of Streptomyces. This organism, indexed I-523 in our culture collection, has been isolated from a soil sample collected from Minō Park, Osaka Prefecture. The antibiotic, which we have named minomycin, possesses highly significant activity against the gram-positive organism and shows some inhibitory effect on Ehrlich ascites tumor and Crocker sarcoma in vitro.
In the present paper, we intend to describe the antibiotic-producing organism and to, report the production, isolation, chemical properties, antimicrobial spectrum, and anti-tumor activities of minomycin.
