膵分泌の基因に関する細胞學的研究

VI. アトロピン注射の影響に就て

抄録

It is well known that atropin controls the discharge of the secretory substance from the gland cell, however the authors have obtained such results as that production of secretion granules in the pancreatic and the peptic cells was controled and its discharge from the peptic cell was not influenced, by the injection of sesame oil into the stomach of the starved rats after the subcutaneous injection of atropin. Then the authors performed the next experiment in which histamine was injected subcutaneously into the starved rats after the subcutaneous injection of atropin, and compared the functional movements of the pancreatic, the peptic cells and the surface cells of the gastric mucous membrane in these two experiments.
According to the results of these experiments, it was made clear that atropin controled the discharge function of the surface cells of the gastric mucosa, but did not effect the pancreatic and the peptic cells directly.
From these results, the facts were demonstrated that the hormone, named Productin (FUJIE), which promotes production of secretion granules in the pancreatic and the peptic cells, is produced in the surface cells of the gastric mucous membrane and the actions of secreted Productin and Gastrin (EDKINS), the splitted product of Productin, which are the production of secretion granules in the pancreatic and the peptic cells and its discharge from the peptic cell, are not effected by atropin.