Consumption of a Buckwheat Protein Extract Retards 7,12-Dimethylbenz[α] anthracene-Induced Mammary Carcinogenesis in Rats

Abstract

  Female rats were examined for the effects of feeding buckwheat protein extract (BWPE) on the development of mammary tumor caused by administration of 7,12-dimethylbenz[α]anthracene. The percentage of rats with palpable mammary tumors and serum estradiol were lower in the BWPE-fed animals than the casein-fed ones, implying that BWPE intake retarded the mammary carcinogenesis by lowering serum estradiol.