Two Novel Diterpenoids, Erinacines H and I from the Mycelia of Hericium erinaceum

Eun Woo LEE; Kazue SHIZUKI; Satoshi HOSOKAWA; Masami SUZUKI; Hiroyuki SUGANUMA; Takahiro INAKUMA; Jingxuan LI; Mayumi OHNISHI-KAMEYAMA; Tadahiro NAGATA; Shoei FURUKAWA; Hirokazu KAWAGISHI

doi:10.1271/bbb.64.2402

Organic Chemistry Regular Papers

Two Novel Diterpenoids, Erinacines H and I from the Mycelia of Hericium erinaceum

Eun Woo LEE, Kazue SHIZUKI, Satoshi HOSOKAWA, Masami SUZUKI, Hiroyuki SUGANUMA, Takahiro INAKUMA, Jingxuan LI, Mayumi OHNISHI-KAMEYAMA, Tadahiro NAGATA, Shoei FURUKAWA, Hirokazu KAWAGISHI

Author information

Eun Woo LEE
Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University
Kazue SHIZUKI
Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University
Satoshi HOSOKAWA
Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University
Masami SUZUKI
Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University
Hiroyuki SUGANUMA
Research Institute, Kagome Co., Ltd.
Takahiro INAKUMA
Research Institute, Kagome Co., Ltd.
Jingxuan LI
Jilin Institute of Biology
Mayumi OHNISHI-KAMEYAMA
National Food Research Institute, Ministry of Agriculture, Forestry and Fisheries
Tadahiro NAGATA
Department of Animal Products, National Institute of Animal Industry-NIAI
Shoei FURUKAWA
Department of Molecular Biology, Gifu Pharmaceutical University
Hirokazu KAWAGISHI
Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University

Keywords: Hericium erinaceum, nerve growth factor, stimulator, diterpenoid

JOURNAL FREE ACCESS

2000 Volume 64 Issue 11 Pages 2402-2405

DOI https://doi.org/10.1271/bbb.64.2402

Details

Abstract

Novel diterpenoids, erinacines H (1) and I (3), were isolated from the cultured mycelia of Hericium erinaceum. The structures of the compounds were determined by interpretation of the spectral data. Erinacine H showed stimulating activity of nerve growth factor (NGF)-synthesis.

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