Effects of Branched Cyclodextrins on the Solubility and Stability of Terpenes

抄録

  In order to investigate the application potential of branched CDs, the solubilizing ability and the stabilizing ability of G2-βCD and GUG-βCD were investigated by using twelve terpenes (d-limonene, myrcene, terpinolene, geraniol, l-menthol, nerol, α-terpineol, citral, d-citronellal, l-perillaldehyde, (R)-l-carvone, and menthone) as guest compounds. G2-βCD and GUG-βCD showed more solubilizing ability for these twelve terpenes than βCD, and the ability of GUG-βCD was almost the same as that of G2-βCD. The stabilizing ability of terpene-GUG-βCD complexes was different from that of G2-βCD. GUG-βCD was superior to G2-βCD, especially in the solid state. This result may have been caused by the difference in structure of side chain, namely the hydroxymethyl group in G2-βCD and the carboxyl group in GUG-βCD.