Unique Occurrence of the 1CF11 Carbohydrate Epitope in Primate Saliva

Shan-Ming YANG; Naoko YOKOI; Yoshihiro KANAMARU; Osamu TAKENAKA; Yasuro ATOJI; Yasuo BUNAI; Isao OHYA; Xong-Guang SONG; Satoshi NAGAOKA; Makoto SHIMIZU; Goverdhan P. SACHDEV

doi:10.1271/bbb.65.714

Biochemistry & Molecular Biology

Unique Occurrence of the 1CF11 Carbohydrate Epitope in Primate Saliva

Shan-Ming YANG, Naoko YOKOI, Yoshihiro KANAMARU, Osamu TAKENAKA, Yasuro ATOJI, Yasuo BUNAI, Isao OHYA, Xong-Guang SONG, Satoshi NAGAOKA, Makoto SHIMIZU, Goverdhan P. SACHDEV

Author information

Shan-Ming YANG
Department of Food Science, Faculty of Agriculture, Gifu University
Naoko YOKOI
Department of Food Science, Faculty of Agriculture, Gifu University
Yoshihiro KANAMARU
Department of Food Science, Faculty of Agriculture, Gifu University
Osamu TAKENAKA
Molecular Biology Section, Primate Research Institute, Kyoto University
Yasuro ATOJI
Division of Veterinary Medicine, Faculty of Agriculture, Gifu University
Yasuo BUNAI
Department of Forensic Medicine, Gifu University School of Medicine
Isao OHYA
Department of Forensic Medicine, Gifu University School of Medicine
Xong-Guang SONG
Department of Food Science, Faculty of Agriculture, Gifu University
Satoshi NAGAOKA
Department of Food Science, Faculty of Agriculture, Gifu University
Makoto SHIMIZU
Department of Applied Biological Chemistry, The University of Tokyo
Goverdhan P. SACHDEV
College of Pharmacy, University of Oklahoma Health Sciences Center

Keywords: 1CF11, monoclonal antibody, saliva, humans, simians

JOURNAL FREE ACCESS

2001 Volume 65 Issue 3 Pages 714-718

DOI https://doi.org/10.1271/bbb.65.714

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Abstract

We examined a large number of individual human and animal saliva samples for the reactivity with 1CF11, a mouse monoclonal antibody previously produced for the characterization of human milk mucin and apparently recognizing a certain carbohydrate antigenic structure shared by various human glycoproteins in secretions. The results obtained here confirm the unique occurrence of 1CF11 epitope in each and every saliva sample from humans and Old world monkeys as well, though a vast variety was observed among individual saliva samples in the immunological reactivity with 1CF11.

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