Department of Mathematics and Science Education, Graduate School of Science, Science University of Tokyo
Hirosato TAKIKAWA
Department of Chemistry, Faculty of Science, Science University of Tokyo
Kenji MORI
Department of Mathematics and Science Education, Graduate School of Science, Science University of Tokyo Department of Chemistry, Faculty of Science, Science University of Tokyo
Gibbilimbols A [(E)-4-(4-decenyl)phenol, 1], B [(E)-4-(3-decenyl)phenol, 2], C [(E)-4-(4-octenyl)phenol, 3] and D [(E)-4-(3-octenyl)phenol, 4] were synthesized by coupling the phenolic parts with the alkyne parts and then reducing the triple bond of the resulting alkynylphenols. These alkenylphenols (1−4) are the cytotoxic and antibacterial constituents of the leaves of a medicinal plant (Piper gibbilimbum) that is used as a traditional medicine in Papua New Guinea.
