Bioscience, Biotechnology, and Biochemistry
Online ISSN : 1347-6947
Print ISSN : 0916-8451
Biochemistry & Molecular Biology Notes
Microencapsulation of Insulin Microcrystals
Sung Hee CHOI, Jai-Hyun KWON, Chan-Wha KIM
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Keywords: insulin, microcrystal, microsphere, poly (lactide-co-glycolide) (PLGA), stability
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2004 Volume 68 Issue 3 Pages 749-752

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Abstract
Insulin microcrystals were encapsulated (microcrystal/PLGA) within poly(lactide-co-glycolide) (PLGA 50:50) by the multiple emulsification solvent evaporation technique and compared with insulin solution microspheres (solution/PLGA) in terms of their morphology, size distribution, drug content, encapsulation efficiency, and stability of insulin during release.
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© 2004 by Japan Society for Bioscience, Biotechnology, and Agrochemistry
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