Laboratory of Bioscience, Faculty of Engineering, Iwate University
Takashi OSADA
Department of Computer and Information Science, Graduate School of Engineering, Iwate University
Ryuzo SHINGAI
Laboratory of Bioscience, Faculty of Engineering, Iwate University Department of Computer and Information Science, Graduate School of Engineering, Iwate University
Serotonin has been implicated in numerous behaviors in a wide variety of animals. We examined the effect of serotonin deficiency, induced by genetic perturbations and cell ablations, on the duration of Caenorhabditis elegans forward movement. Mutants with defective serotonin biosynthesis or worms with ablated serotonergic neurons showed a markedly decreased duration of forward movement, suggesting involvement of this neuromodulator in the regulation of the duration of worm locomotion.
