Bioscience, Biotechnology, and Biochemistry
Online ISSN : 1347-6947
Print ISSN : 0916-8451
Food & Nutrition Science Notes
Effect of Royal Jelly on Bisphenol A-Induced Proliferation of Human Breast Cancer Cells
Mako NAKAYAHiroyuki ONDAKyoko SASAKIAkiko YUKIYOSHIHirofumi TACHIBANAKoji YAMADA
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2007 Volume 71 Issue 1 Pages 253-255

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Abstract

Royal jelly is known as a functional food containing many useful minerals. In this study, we found an anti-environmental estrogen activity of royal jelly. Bisphenol A (BPA) is an environmental estrogen that stimulates proliferation of human breast cancer MCF-7 cells. Royal jelly inhibited the growth-promoting effect of BPA on MCF-7 cells, even though it did not affect the proliferation of cells in the absence of BPA. In addition, this inhibiting effect of royal jelly was heat-stable.

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© 2007 by Japan Society for Bioscience, Biotechnology, and Agrochemistry
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