Abstract
New nematicides named fumiquinones A (1) and B (2), together with spinulosin (3), LL-S490β (4), and pseurotin A (5), were isolated from Aspergillus fumigatus and their structures were established by spectroscopic methods including 2D-NMR. Compound 1 showed effective nematicidal activities against Bursaphelenchus xylophilus and Pratylenchus penetrans without inhibiting plant growth except for lettuce seedlings. Compound 2 showed effective nematicidal activity against B. xylophilus, but had no inhibitory activity against P. penetrans. Compounds 3–5 showed effective nematicidal activities against B. xylophilus without any plant growth inhibition. Compounds 1–5 had no nematicidal activity against Caenorhabditis elegans. This is the first report of the nematicidal activities of compounds 3–5.
