Inconspicamide, New N-Acylated Serinol from the Marine Sponge Stelletta inconspicua

Reiko UEOKA; Tsuyoshi FUJITA; Takashi IWASHITA; Rob. W. M. van SOEST; Shigeki MATSUNAGA

doi:10.1271/bbb.80457

Organic Chemistry Note

Inconspicamide, New N-Acylated Serinol from the Marine Sponge Stelletta inconspicua

Reiko UEOKA, Tsuyoshi FUJITA, Takashi IWASHITA, Rob. W. M. van SOEST, Shigeki MATSUNAGA

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Keywords: cytotoxic metabolite, marine sponge, amide

JOURNAL FREE ACCESS

2008 Volume 72 Issue 11 Pages 3055-3058

DOI https://doi.org/10.1271/bbb.80457

Biosci. Biotechnol. Biochem. : Vol. 73 (2009) No. 3 pp.2009E1

View "Advance Publication" version (November 7, 2008).

Biosci. Biotechnol. Biochem. : Vol. 73 (2009) No. 5 pp.2009E2

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Abstract

A new N-acylated serinol, inconspicamide (1), was isolated from the marine sponge, Stelletta inconspicua, together with a glyceryl ether (2). Their structures were determined on the basis of spectroscopic data and the modified Mosher analysis. They exhibited moderate cytotoxic activity against HeLa human cervical cancer cells.

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