Antioxidant Activity of Butane Type Lignans, Secoisolariciresinol, Dihydroguaiaretic Acid, and 7,7′-Oxodihydroguaiaretic Acid

Satoshi YAMAUCHI; Toshiya MASUDA; Takuya SUGAHARA; Yuya KAWAGUCHI; Maya OHUCHI; Tatsushi SOMEYA; Jun AKIYAMA; Shiori TOMINAGA; Manami YAMAWAKI; Taro KISHIDA; Koichi AKIYAMA; Masafumi MARUYAMA

doi:10.1271/bbb.80461

Organic Chemistry Regular Papers

Antioxidant Activity of Butane Type Lignans, Secoisolariciresinol, Dihydroguaiaretic Acid, and 7,7′-Oxodihydroguaiaretic Acid

Satoshi YAMAUCHI, Toshiya MASUDA, Takuya SUGAHARA, Yuya KAWAGUCHI, Maya OHUCHI, Tatsushi SOMEYA, Jun AKIYAMA, Shiori TOMINAGA, Manami YAMAWAKI, Taro KISHIDA, Koichi AKIYAMA, Masafumi MARUYAMA

著者情報

キーワード: lignan, antioxidant activity, dihydroguaiaretic acid

ジャーナルフリー

2008 年 72 巻 11 号 p. 2981-2986

DOI https://doi.org/10.1271/bbb.80461

View "Advance Publication" version (November 7, 2008).

詳細

抄録

The antioxidant activity of butane-type lignans was evaluated. Secoisolariciresinol (SECO) and dihydroguaiaretic acid (DGA) showed higher radical scavenging activity than that of 7,7′-dioxodihydroguaiaretic acid (ODGA). SECO and DGA inhibited the oxidation of unsaturated fatty acid. Both enantiomers of DGA were also lipoxygenase inhibitors, but neither enantiomer of SECO inhibited the lipoxygenase activity.

責任著者(Corresponding author)

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