29-Norcucurbitacin Derivatives Isolated from the Indonesian Medicinal Plant, Phaleria macrocarpa (Scheff.) Boerl.

Dikdik KURNIA; Kohki AKIYAMA; Hideo HAYASHI

doi:10.1271/bbb.70627

Organic Chemistry Notes

29-Norcucurbitacin Derivatives Isolated from the Indonesian Medicinal Plant, Phaleria macrocarpa (Scheff.) Boerl.

Dikdik KURNIA, Kohki AKIYAMA, Hideo HAYASHI

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Keywords: Phaleria macrocarpa (Scheff.) Boerl., medicinal plant, Thymelaeaceae: norcucurbitacin, desacetylfevicordin A

JOURNAL FREE ACCESS

2008 Volume 72 Issue 2 Pages 618-620

DOI https://doi.org/10.1271/bbb.70627

View "Advance Publication" version (February 7, 2008).

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Abstract

The new 29-norcucurbitacin, desacetylfevicordin A (1), together with three known 29-norcucurbitacin derivatives (2–4) were isolated from seeds of the Indonesian medicinal plant, Phaleria macrocarpa (Scheff.) Boerl. The structures of 1–4 were elucidated on the basis of spectroscopic analyses and chemical transformation. These compounds exhibited toxicity against the brine shrimp (Artemia salina).

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