Published: May 23, 2008Received: February 12, 2008Available on J-STAGE: May 23, 2008Accepted: February 26, 2008
Advance online publication: May 07, 2008
Revised: -
Uroporphyrinogen decarboxylase (HemE) is important due to its location at the first branch-point in tetrapyrrole biosynthesis. We detected a complex formation between full-length polypeptides of HtpG and HemE by biochemical studies in vivo and in vitro. The interaction suppressed the enzyme activity, suggesting a regulatory role of HtpG in tetrapyrrole biosynthesis.
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