Bioscience, Biotechnology, and Biochemistry
Online ISSN : 1347-6947
Print ISSN : 0916-8451
Food & Nutrition Science Notes
Effects of Long-Term Administration of Royal Jelly on Pituitary Weight and Gene Expression in Middle-Aged Female Rats
Yukio NARITAShozo OHTAKazu-Michi SUZUKITomoko NEMOTOKeiko ABESatoshi MISHIMA
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JOURNAL FREE ACCESS

2009 Volume 73 Issue 2 Pages 431-433

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Abstract

To determine the effects of ingested royal jelly (RJ) on the pituitary in middle-aged female rats, we performed a long-term RJ administration test. Several animals showed age-related increases in pituitary weight, and RJ administration compensated for the increase. RJ tended to down-regulate prolactin mRNA and up-regulated thyroid-stimulating hormone β mRNA in the pituitary. This suggests that RJ compensates for age-associated decline in pituitary functions.

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© 2009 by Japan Society for Bioscience, Biotechnology, and Agrochemistry
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