Bioscience, Biotechnology, and Biochemistry
Online ISSN : 1347-6947
Print ISSN : 0916-8451
Organic Chemistry Regular Papers
Asymmetric Synthesis and Sensory Evaluation of Sedanenolide
Daichi OGUROHidenori WATANABE
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2011 年 75 巻 8 号 p. 1502-1505

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The synthesis and sensory evaluation of enantiomeric sets of sedanenolide (1) and 3-butylphthalide (3) are described. The asymmetric synthesis was achieved via the intramolecular Diels-Alder reaction of chiral propargylester (5) which was prepared from optically active propargyl alcohol (4) and 2,4-pentadienoic acid. The sensory evaluation of these enantiomers revealed that there were distinct differences between their aroma character and odor threshold.
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© 2011 by Japan Society for Bioscience, Biotechnology, and Agrochemistry
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