Achillinin A, a Cytotoxic Guaianolide from the Flower of Yarrow, Achillea millefolium

Yong LI; Man-Li ZHANG; Bin CONG; Si-Ming WANG; Mei DONG; Françoise SAURIOL; Chang-Hong HUO; Qing-Wen SHI; Yu-Cheng GU; Hiromasa KIYOTA

doi:10.1271/bbb.110234

Organic Chemistry Regular Papers

Achillinin A, a Cytotoxic Guaianolide from the Flower of Yarrow, Achillea millefolium

Yong LI, Man-Li ZHANG, Bin CONG, Si-Ming WANG, Mei DONG, Françoise SAURIOL, Chang-Hong HUO, Qing-Wen SHI, Yu-Cheng GU, Hiromasa KIYOTA

著者情報

キーワード: Achillea millefolium, flower, guaianolide, isolation

ジャーナルフリー

2011 年 75 巻 8 号 p. 1554-1556

DOI https://doi.org/10.1271/bbb.110234

View "Advance Publication" version (August 7, 2011).

詳細

抄録

Achillinin A (2β,3β-epoxy-1α,4β,10α-trihydroxyguai-11(13)-en-12,6α-olide, 1), a new guaianolide isolated from the flower of Achillea millefolium, exhibited potential antiproliferative activity to A549, RERF-LC-kj and QG-90 cells with 50% inhibitory concentration (IC₅₀) values of 5.8, 10 and 0.31 μM, respectively.

責任著者(Corresponding author)

J-STAGEへの登録はこちら（無料）