Suppressive Effects by Leaves of the Dypsis lutescens Palm on Fat Accumulation in 3T3-L1 Cells and Fat Absorption in Mice

Tomoyuki KOYAMA; Mitsuyoshi MIYATA; Tomio NISHIMURA; Kazunaga YAZAWA

doi:10.1271/bbb.110574

Food & Nutrition Science Notes

Suppressive Effects by Leaves of the Dypsis lutescens Palm on Fat Accumulation in 3T3-L1 Cells and Fat Absorption in Mice

Tomoyuki KOYAMA, Mitsuyoshi MIYATA, Tomio NISHIMURA, Kazunaga YAZAWA

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Keywords: Dypsis lutescens, anti-obesity effect, lipase inhibitor, 3T3-L1, high-fat diet

JOURNAL FREE ACCESS

2012 Volume 76 Issue 1 Pages 189-192

DOI https://doi.org/10.1271/bbb.110574

View "Advance Publication" version (January 7, 2012).

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Abstract

The methanol extract of Dypsis lutescens leaves showed inhibitory effects on lipase activity in vitro and on triglyceride accumulation in 3T3-L1 pre-adipocytes. Further experiments using the extract on mice demonstrated a suppressive effect on the postprandial elevation of blood triglyceride level and an anti-obesity effect on obese mice induced by a high-fat diet. D. lutescens will accordingly be useful for preventing obesity.

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